Members


Chemistry: Marta Artola

Assistant ProfessorMedical Biochemistry,
Leiden Institute of Chemistry

My group rationally develops biochemical tools including substrates, inhibitors and protein degraders for glyco-processing enzymes. We apply these tools to investigate biological processes and develop therapeutic strategies.

m.e.artola@lic.leidenuniv.nl
https://www.universiteitleiden.nl

Organic chemistry, chemical biology, and medical biochemistry

Analytics: Noortje de Haan

Assistant Professor Tissue Glycomics,
Center for Proteomics and Metabolomics, Leiden University Medical Center

Inspired by the huge impact that small changes in glycan structures can have on human health, my group is dedicated to developing the tools to study glycosylation in human tissues in health and disease. Our key technologies are nano-liquid chromatography coupled to mass spectrometry (nanoLC-MS) and mass spectrometry imaging (MSI).

n.de_haan@lumc.nl
https://cpm.lumc.nl

Glyco MSI; Released glycan profiling cells and tissues

Analytics: Alan Moran

Sr. Scientist, Johnson & Johnson Innovative Medicine

linkedin.com/in/moranalan


Glycoconjugates, vaccines, glycosylation characterization

Analytics: Manfred Wuhrer

Professor Proteomics and Glycomics
Center for Proteomics and Metabolomics, Leiden University Medical Center

My group develops and applies mass spectrometric techniques that allow protein glycosylation analysis at high sensitivity and often in a high-throughput fashion. These methods are applied to characterize e.g. immunoglobulin glycosylation in autoimmunity, infection and vaccination, but also to characterize the structure and function of the glycosylation of biopharmaceuticals.

m.wuhrer@lumc.nl
https://cpm.lumc.nl

Antibodies, biopharmaceuticals, glycosylation profiling